TRANSCRANIAL DIRECT CURRENT STIMULATION FOR THE MANAGEMENT OF FATIGUE IN PATIENTS WITH MULTIPLE SCLEROSIS. SYSTEMATIC REVIEW

Abstract

Introduction: Multiple Sclerosis (MS) is an autoimmune neurological disease that affects more than a million pe-ople, fatigue being its most disabling symptom. Direct transcranial current (DTC) is a type of non-invasive stimu-lation (NIBS) that has been shown to be beneficial in numerous neurological disorders. Objective: to analyze the effectiveness of DTC in treating fatigue in people with MS. Material and method: a systematic review of different clinical trials has been carried out between June and July 2020 in the databases: PEDro, Pubmed and WOS. In order to obtain up-to-date information, the search was limited to studies from the last 10 years. Furthermore, only articles that were randomized clinical trials (RCTs) or clinical trials (RCTs) have been included. Results: a total of twelve articles were selected, of which six chose the dorsolateral prefrontal cortex (DLPFC), four articles chose the primary somatosensory cortex (S1), one article chose the parietal cortex (PC), and one article chose the cortex motor (CM). All these studies have shown to have beneficial effects in modifying the symptom of fatigue in patients with MS. Conclusion: although the results obtained on CDT have been beneficial in modifying the symptom of fatigue, it is necessary to unify the action protocols and try to determine which could be the most effective method of action in modifying said symptom in patients suffering from of EM.